Medications used in spinal cord injuries are used to treat the symptoms experienced by patients. There is no medication to cure SCI.

Methylprednisolone (Medrol) is a steroid medication and is one option for treatment of spinal cord injury. If it is given within eight hours after injury, it can decrease damage to nerve cells and reduce inflammation near the site of the injury.

• Antidepressants- these drugs are used to treat various psychological disorders, such as depression, anxiety, obsessive-compulsive disorder (OCD), and panic disorders. Antidepressants are also sometimes used to treat chronic pain syndromes and migraine headaches. They may have several side effects that patients find intolerable; if this occurs, another antidepressant from a different family of antidepressants may be tried.
• Narcotics- narcotics are strong painkillers given to relieve severe pain, and may be used to treat many different types of pain. Narcotics may be habit-forming if taken for an extended period of time. The patient may also build up a tolerance to the drug, so that larger doses of the drug are needed to achieve the same benefit. 
• Other Pain Relievers-milder pain relievers, such as acetaminophen (Tylenol), ASA (aspirin), and Ibuprofen (Motrin, Advil) may be used to treat less severe pain experienced by patients with SCI. Ibuprofen and ASA can cause bleeding in some patients.
• Muscle Relaxants-Drugs in this category may be used to relieve muscle pain and spasm. They may have some undesirable side effects, such as fatigue.
• Antibiotics-Patients with SCI may be more prone to certain infections, such as pneumonia and urinary tract infections. Antibiotics are used to treat these infections.
• Laxatives and Stool Softeners-Patients with SCI are prone to constipation due to immobility. These medications are used to soften stools and stimulate the bowel, and are usually used as part of a regular bowel program.